Article
Immunohistochemical analysis of Clara cell secretory protein expression in a transgenic model of mouse lung carcinogenesis.
Toxicology - 3 May 2003
Hicks Sarah M, Vassallo Jeffrey D, Dieter Matthew Z, Lewis Cindy L, Whiteley Laurence O, Fix Andrew S, Lehman-McKeeman Lois D
Abstract excerpt
Immunohistochemical methods have been widely used to determine the histogenesis of spontaneous and chemically-induced mouse lung tumors. Typically, antigens for either alveolar Type II cells or bronchiolar epithelial Clara cells are studied. In the present work, the morphological and immunohistochemical phenotype of a transgenic mouse designed to develop lung tumors arising from Clara cells was evaluated. In this...
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