Article
Septins have a dual role in controlling mitotic exit in budding yeast.
Current biology : CB - 15 Apr 2003
Castillon Guillaume A, Adames Neil R, Rosello Caroline H, Seidel Hannah S, Longtine Mark S, Cooper John A, Heil-Chapdelaine Richard A
Abstract excerpt
In Saccharomyces cerevisiae, the spindle position checkpoint ensures that cells do not exit mitosis until the mitotic spindle moves into the mother/bud neck and thus guarantees that each cell receives one nucleus [1-6]. Mitotic exit is controlled by the small G protein Tem1p. Tem1p and its GTPase activating protein (GAP) Bub2p/Bfa1p are located on the daughter-bound spindle pole body. The GEF Lte1p is located in...
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