Article
A Novel Hyperactive Nud1 Mitotic Exit Network Scaffold Causes Spindle Position Checkpoint Bypass in Budding Yeast.
Cells - 24 Dec 2021
Vannini Michael, Mingione Victoria R, Meyer Ashleigh, Sniffen Courtney, Whalen Jenna, Seshan Anupama
Abstract excerpt
Mitotic exit is a critical cell cycle transition that requires the careful coordination of nuclear positioning and cyclin B destruction in budding yeast for the maintenance of genome integrity. The mitotic exit network (MEN) is a Ras-like signal transduction pathway that promotes this process during anaphase. A crucial step in MEN activation occurs when the Dbf2-Mob1 protein kinase complex associates with the...
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