Temporal coupling of spindle disassembly and cytokinesis is disrupted by deletion of LTE1 in budding yeast.

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Article

Temporal coupling of spindle disassembly and cytokinesis is disrupted by deletion of LTE1 in budding yeast.

Cell cycle (Georgetown, Tex.) - 1 Jun 2004

Jensen Sanne, Johnson Anthony L, Johnston Leland H, Segal Marisa

Abstract excerpt

The mitotic exit network (MEN) is a signal transduction cascade that controls exit from mitosis in budding yeast by triggering the nucleolar release and hence activation of the Cdc14 phosphatase. Activation of the MEN is tightly coordinated with spindle position in such a way that Cdc14 is only fully released upon spindle pole body (SPB) migration into the daughter cell. This temporal regulation of the MEN has...

Topics

Actomyosin
Cytokinesis
Gene Deletion
Genotype
Guanine Nucleotide Exchange Factors
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Signal Transduction
Spindle Apparatus

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Open in PubMed

Identifiers

PMID: 15197338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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