Article
Smoking and selected DNA repair gene polymorphisms in controls: systematic review and meta-analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2010
Hodgson M Elizabeth, Poole Charles, Olshan Andrew F, North Kari E, Zeng Donglin, Millikan Robert C
Abstract excerpt
BACKGROUND: When the case-only study design is used to estimate statistical interaction between genetic (G) and environmental (E) exposures, G and E must be independent in the underlying population, or the case-only estimate of interaction (COR) will be biased. Few studies have examined the occurrence of G-E association in published control group data. METHODS: To examine the assumption of G-E independence in...
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