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Article

Candidate-gene association studies with pedigree data: controlling for environmental covariates.

Genetic epidemiology - 1 May 2003

Slager S L, Schaid D J, Wang L, Thibodeau S N

Abstract excerpt

Case-control studies provide an important epidemiological tool to evaluate candidate genes. There are many different study designs available. We focus on a more recently proposed design, which we call a multiplex case-control (MCC) design. This design compares allele frequencies between related cases, each of whom are sampled from multiplex families, and unrelated controls. Since within-family genotype...

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PMID: 12687644
DOI: 10.1002/gepi.10228

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MCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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