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Article

Evaluation of candidate genes in case-control studies: a statistical method to account for related subjects.

American journal of human genetics - 1 Jun 2001

Slager S L, Schaid D J

Abstract excerpt

Traditional case-control studies provide a powerful and efficient method for evaluation of association between candidate genes and disease. The sampling of cases from multiplex pedigrees, rather than from a catchment area, can increase the likelihood that genetic cases are selected. However, use of all the related cases without accounting for their biological relationship can increase the type I error rate of the...

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Identifiers

PMID: 11353403
DOI: 10.1086/320608
PMCID: PMC1226132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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