Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tests for genetic association using family data.

Genetic epidemiology - 1 Feb 2002

Shih Mei-Chiung, Whittemore Alice S

Abstract excerpt

We use likelihood-based score statistics to test for association between a disease and a diallelic polymorphism, based on data from arbitrary types of nuclear families. The Nonfounder statistic extends the transmission disequilibrium test (TDT) to accommodate affected and unaffected offspring, mi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Family Health
Share to Founder Effect
Share to Genetic Diseases, Inborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Likelihood Functions

Share to Linkage Disequilibrium

Share to Models, Statistical

Share to Prostatic Neoplasms

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 11788959
DOI: 10.1002/gepi.0151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11788959-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tests for genetic association using family data.PMID 11788959Read ↗

Detection of disease genes by use of family data. II. Application to nuclear families.Semantic proximity Read ↗

Implementing a unified approach to family-based tests of association.Semantic proximity Read ↗

Sequence robust association test for familial data.Semantic proximity Read ↗

Detection of disease genes by use of family data. I. Likelihood-based theory.Semantic proximity Read ↗

Disease associations and family-based tests.Semantic proximity Read ↗

Disease associations and family-based tests.Semantic proximity Read ↗

Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits.Semantic proximity Read ↗

Genetic association mapping based on discordant sib pairs: the discordant-alleles test.Semantic proximity Read ↗

Nonparametric tests of association of multiple genes with human disease.Semantic proximity Read ↗

Application of a novel score test for genetic association incorporating gene-gene interaction suggests functionality for prostate cancer susceptibility regions.Semantic proximity Read ↗

General score tests for associations of genetic markers with disease using cases and their parents.Semantic proximity Read ↗

A generalized family-based association test for dichotomous traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.