Article
[Mutation of p53 gene and expression of alphafetoprotein during hepatocarcinogenesis].
Zhonghua yi xue za zhi - 1 Aug 1994
Zou H Q, Tang Z Y, Ye S L
Abstract excerpt
To investigate the expression of mutant p53 protein (mP53) and alpha-fetoprotein (AFP) during hepatocarcinogenesis, we detected immunohistochemically the specimens from 4 cases of normal human liver, 5 of cirrhosis, 5 of adenomatous hyperplasia (AH), and 16 of hepatocellular carcinoma (HCC) (by Edmondson classification. The 4 cases with normal liver showed negative mP53 and AFP. Four of the 5 cirrhosis cases were...
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