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Article

Application of fluorescence polarization to enzyme assays and single nucleotide polymorphism genotyping: some recent developments.

Combinatorial chemistry & high throughput screening - 1 May 2003

Nikiforov Theo T, Simeonov Anton M

Abstract excerpt

This article describes some recent developments in the field of fluorescence polarization (FP) as applied to enzyme assays and single nucleotide polymorphism (SNP) genotyping. First, we present our recent progress on the application of fluorescence polarization to high throughput screening (HTS). We show how the use of a 2-thiopyridinone-based, mixed disulfide biotinylation reagent can shorten the assay time of...

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PMID: 12678699
DOI: 10.2174/138620703106298383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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