Article
Genotyping single-nucleotide polymorphisms by the invader assay with dual-color fluorescence polarization detection.
Clinical chemistry - 1 Aug 2001
Hsu T M, Law S M, Duan S, Neri B P, Kwok P Y
Abstract excerpt
BACKGROUND: The PCR-Invader assay is a robust, homogeneous assay that has been shown to be highly sensitive and specific in genotyping single-nucleotide polymorphism (SNP) markers. In this study, we introduce two changes to improve the assay: (a) we streamline the PCR-Invader method by assaying b...
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