Article
Molecular dissection of Fc gamma receptor-mediated phagocytosis.
Immunology letters - 1 Jan 1995
Indik Z K, Park J G, Hunter S, Mantaring M, Schreiber A D
Abstract excerpt
Using an experimental model in COS-1 cells, we have examined the structural requirements for phagocytosis of IgG-sensitized cells by Fc gamma receptors. We have established that isoforms of each of the 3 classes of the Fc gamma receptors, Fc gamma RI, Fc gamma RII and Fc gamma RIII, are able to t...
Topics
- Amino Acid Sequence
- Animals
- Cells, Cultured
- Humans
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Phagocytosis
- Receptors, IgG
- Recombinant Fusion Proteins
- Signal Transduction
- Structure-Activity Relationship