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Article

Drosophila p53 preserves genomic stability by regulating cell death.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 2003

Sogame Naoko, Kim Misoo, Abrams John M

Abstract excerpt

When animal cells are exposed to stressful conditions, the tumor suppressor protein p53 restrains growth by promoting an arrested cell cycle or initiating a cell death program. How these distinct fates are specified through the action of a single protein is not known. To study its functions in vivo we produced a targeted mutation at the Drosophila p53 (Dmp53) locus. We show that Dmp53 is required for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12672954
DOI: 10.1073/pnas.0736384100
PMCID: PMC153618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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