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Article

In vivo p53 function is indispensable for DNA damage-induced apoptotic signaling in Drosophila.

FEBS letters - 28 Aug 2003

Lee Jun Hee, Lee Eunji, Park Jeehye, Kim Euysoo, Kim Jaeseob, Chung Jongkyeong

Abstract excerpt

p53 is a representative tumor suppressor whose dysfunction is a major cause of human cancer syndrome. Here we isolated flies lacking Dmp53, which encodes the single Drosophila orthologue of mammalian p53 family. Dmp53 null mutants well developed into adults, only displaying mild defects in longev...

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PMID: 12935877
DOI: 10.1016/s0014-5793(03)00771-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12935877-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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