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Article

Genetic diversity and natural selection of Duffy binding protein of Plasmodium vivax Korean isolates.

Acta tropica - 1 Jan 2013

Ju Hye-Lim, Kang Jung-Mi, Moon Sung-Ung, Bahk Young-Yil, Cho Pyo-Yun, Sohn Woon-Mok, Park Yun-Kyu, Park Jae-Won, Kim Tong-Soo, Na Byoung-Kuk

Abstract excerpt

Plasmodium vivax Duffy binding protein (PvDBP) is a micronemal type I membrane protein that plays an essential role in erythrocyte invasion of merozoites. PvDBP is a prime blood stage vaccine candidate antigen against P. vivax, but its polymorphic nature represents a major obstacle to the successful design of a protective vaccine against vivax malaria. In this study, we analyzed the genetic polymorphism and...

Topics

Antigens, Protozoan
Epitopes, B-Lymphocyte
Epitopes, T-Lymphocyte
Humans
Malaria, Vivax
Molecular Sequence Data
Plasmodium vivax
Polymorphism, Single Nucleotide
Protozoan Proteins
Receptors, Cell Surface

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Republic of Korea

Selection, Genetic

Sequence Analysis, DNA

Source

Identifiers

PMID: 23031445
DOI: 10.1016/j.actatropica.2012.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23031445-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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