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Article

Polymorphism patterns in Duffy-binding protein among Thai Plasmodium vivax isolates.

Malaria journal - 26 Jun 2008

Gosi Panita, Khusmith Srisin, Khalambaheti Thareerat, Lanar David E, Schaecher Kurt E, Fukuda Mark M, Miller Scott R

Abstract excerpt

BACKGROUND: The Duffy-binding protein II of Plasmodium vivax (PvDBPII) has been considered as an attractive target for vaccine-mediated immunity despite a possible highly polymorphic nature. Among seven PvDBP domains, domain II has been shown to exhibit a high rate of nonsynonymous polymorphism, which has been suggested to be a potential immune (antibody binding) evasion mechanism. This study aimed to determine...

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Source

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Identifiers

PMID: 18582360
DOI: 10.1186/1475-2875-7-112
PMCID: PMC2443374

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Source receipt: pubmed, retrieved 7 Sept 2026.

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