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Article

Bioavailability factors of isoniazid in fast and slow acetylators, healthy volunteers.

Acta poloniae pharmaceutica - 1 Jan 2000

Augustynowicz-Kopeć Ewa, Zwolska Zofia

Abstract excerpt

The INH metabolism mainly involves acetylation to acetyloisoniazid by a non inducible hepatic enzyme N-acetyltransferase. Examples of drugs acetylated by this enzymatic system are: isoniazid, sulphadimidine. hydrallazine, dapson and sulphapyridine. The rate of acetylation is constant in any individual but varies in different patients. People are characterized as rapid or slow acetylators with slow acetylation...

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Source

Identifiers

PMID: 12669770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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