The type of isoniazid acetylation in tuberculosis patients treated at National Tuberculosis and Lung Diseases Research Institute.

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Article

The type of isoniazid acetylation in tuberculosis patients treated at National Tuberculosis and Lung Diseases Research Institute.

Acta poloniae pharmaceutica - 1 Jan 2000

Augustynowicz-Kopeć Ewa, Zwolska Zofia

Abstract excerpt

The research has dealt with types of acetylation in 237 TB patients treated by standard course of chemotherapy with a 300 mg dose of INH at the National Tuberculosis and Lung Diseases Research Institute in Warsaw (NTLDRI). Blood samples were taken before (time 0) and 1, 3, 6 and 24 h after drug administration. Plasma concentrations of isoniazid were determined with biological methods. Two indicators of...

Topics

Acetylation
Adult
Aged
Aged, 80 and over
Antitubercular Agents
Area Under Curve
Biological Availability
Female
Humans
Isoniazid
Male
Middle Aged
Phenotype
Tuberculosis

Source

Open in PubMed

Identifiers

PMID: 12669768

Provenance

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