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Article

Hypotension and reduced catecholamines in neuropeptide Y transgenic rats.

Hypertension (Dallas, Tex. : 1979) - 1 May 2003

Michalkiewicz Mieczyslaw, Knestaut Kriss M, Bytchkova Elena Yu, Michalkiewicz Teresa

Abstract excerpt

The neurons that control blood pressure express neuropeptide Y. Administered centrally, this neuropeptide reduces blood pressure and anxiety, together with lowering sympathetic outflow. The generation of neuropeptide Y transgenic rats overexpressing this peptide, under its natural promoter, has allowed us to examine the role of endogenous neuropeptide Y in the long-term control of blood pressure by the...

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PMID: 12668588
DOI: 10.1161/01.HYP.0000066623.64368.4E

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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