Article
Prognostic value of overexpression of p53 in human ovarian carcinoma patients receiving cisplatin.
Cancer letters - 31 Mar 2003
Nakayama Kentaro, Takebayashi Yuji, Nakayama Satoru, Hata Kohkichi, Fujiwaki Ritsuto, Fukumoto Manabu, Miyazaki Kohji
Abstract excerpt
A major obstacle to the treatment of ovarian carcinoma is intrinsic/acquired resistance to cisplatin-based chemotherapy. The clinical significance of p53 overexpression in patients with ovarian carcinoma is still controversial. The aim of this study was to investigate the independent prognostic significance of p53 overexpression in patients with ovarian carcinoma who are treated with cisplatin. We retrospectively...
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