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Article

p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: a molecular and immunohistochemical study.

British journal of cancer - 1 Jan 1997

Buttitta F, Marchetti A, Gadducci A, Pellegrini S, Morganti M, Carnicelli V, Cosio S, Gagetti O, Genazzani A R, Bevilacqua G

Abstract excerpt

Chemotherapeutic management of ovarian cancers is a difficult task as these neoplasms show significant differences in chemosensitivity, even if they share identical clinicopathological features. The present study was undertaken to investigate the prognostic and predictive role of p53 alterations in ovarian cancer. To this end, using different technical approaches, i.e. genetic and immunohistochemical analyses, we...

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Identifiers

PMID: 9010031
DOI: 10.1038/bjc.1997.38
PMCID: PMC2063269

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Source receipt: pubmed, retrieved 7 Sept 2026.

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