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Article

Expression of factors involved in regulation of DNA mismatch repair- and apoptosis pathways in ovarian cancer patients

1 Mar 2007

Abstract excerpt

A major obstacle in treatment of ovarian cancer is intrinsic or acquired drug resistance causing failure of chemotherapy followed by a poor clinical outcome. Drug resistance of ovarian carcinoma can be caused by dysregulation of cellular factors involved in regulation of apoptosis and DNA repair pathways. In this study, 73 ovarian carcinoma specimens obtained before and after chemotherapy were analysed by...

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PMID: 17273726
DOI: 10.3892/or.17.3.505

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