Article
Expression and mutation of p53 in tumor effusion cells of patients with ovarian carcinoma: response to cisplatin-based chemotherapy.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2000
Bar J K, Harłozińska A, Popiela A, Noga L
Abstract excerpt
p53 alterations are considered as one of the most important factors responsible for drug resistance in ovarian carcinomas, although the relationship between p53 gene status and response to cisplatin-based chemotherapy in ovarian cancer patients remains unclear. The aim of the study was to evaluate the relationship between p53 protein accumulation, p53 gene mutation and response to cisplatin-based chemotherapy in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
