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Article

NF2 tumor suppressor gene: a comprehensive and efficient detection of somatic mutations by denaturing HPLC and microarray-CGH.

Neuromolecular medicine - 1 Jan 2003

Szijan Irene, Rochefort Daniel, Bruder Carl, Surace Ezequiel, Machiavelli Gloria, Dalamon Viviana, Cotignola Javier, Ferreiro Veronica, Campero Alvaro, Basso Armando, Dumanski Jan P, Rouleau Guy A

Abstract excerpt

The NF2 tumor suppressor gene, located in chromosome 22q12, is involved in the development of multiple tumors of the nervous system, either associated with neurofibromatosis 2 or sporadic ones, mainly schwannomas and meningiomas. In order to evaluate the role of the NF2 gene in sporadic central nervous system (CNS) tumors, we analyzed NF2 mutations in 26 specimens: 14 meningiomas, 4 schwannomas, 4 metastases, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12665675
DOI: 10.1385/NMM:3:1:41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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