Article
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Jun 2011
Alcaro Stefano, Alteri Claudia, Artese Anna, Ceccherini-Silberstein Francesca, Costa Giosuè, Ortuso Francesco, Parrotta Lucia, Perno Carlo Federico, Svicher Valentina
Abstract excerpt
In recent years relevant progress has been made in the treatment of HIV-1 with a consequent decrease in mortality. The availability of potent antiretroviral drugs and the ability of viral load assays that accurately evaluate the true level of viral replication, have led to a better understanding of pathogenesis of the disease and how to obtain improved therapeutic profiles. The highly active antiretroviral...
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