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Article

Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors.

Antiviral therapy - 1 Jan 2009

Tambuyzer Lotke, Azijn Hilde, Rimsky Laurence T, Vingerhoets Johan, Lecocq Pierre, Kraus Guenter, Picchio Gaston, de Béthune Marie-Pierre

Abstract excerpt

BACKGROUND: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important component of antiretroviral therapy for HIV type-1 (HIV-1)-infected patients. Development of NNRTI resistance can lead to treatment failure and is conferred by the presence of specific resistance-associated mutations (RAMs) in the reverse transcriptase. In addition to the widely used list of NNRTI RAMs provided by the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19320243

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