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Article

Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease.

Coronary artery disease - 1 Apr 2003

Winter Julian P, Gong YunYun, Grant Peter J, Wild Christopher P

Abstract excerpt

OBJECTIVE: Oxidative stress is implicated in the pathogenesis of many human diseases including atherosclerosis. Human glutathione peroxidase 1 (hgpx1) participates in limiting cellular damage caused by oxidation. A characteristic polyalanine sequence polymorphism in exon 1 of hgpx1 produces three alleles with five, six or seven alanine (ALA) repeats in this sequence. The objective of this study was to determine...

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Identifiers

PMID: 12655278
DOI: 10.1097/00019501-200304000-00007

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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