Article
Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease.
Journal of cardiovascular risk - 1 Feb 2002
Wang Xing Li, Greco Marissa, Sim Ah Siew, Duarte Natalia, Wang Jian, Wilcken David E L
Abstract excerpt
BACKGROUND: While genetic variation accounts for a large proportion of interindividual differences in coronary artery disease (CAD) development, environmental factors such as cigarette smoking may genotype-dependently initiate or accelerate the risk. Glutathione S-transferase mu1 (GSTM1) is one of the GST isoenzymes and contributes to the detoxification process of organic compounds produced by cigarette smoking....
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