Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart Failure

2 Jun 2019

Abstract excerpt

Disturbed redox balance in heart failure (HF) might contribute to impairment of cardiac function, by oxidative damage, or by regulation of cell signaling. The role of polymorphism in glutathione transferases (GSTs), involved both in antioxidant defense and in regulation of apoptotic signaling pathways in HF, has been proposed. We aimed to determine whether GST genotypes exhibit differential risk effects between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Folate and B Vitamins Research
Share to Genomics, phytochemicals, and oxidative stress
Share to Glutathione Transferases and Polymorphisms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31275451
DOI: 10.1155/2019/6984845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart FailurePMID 31275451Read ↗

Association of GSTT1/GSTM1 and ApoE variants with left ventricular diastolic dysfunction in thalassaemia major patients.Semantic proximity Read ↗

Oxidative Stress and DNA Damage Biomarkers in Heart Failure: A Systematic Review and Meta-AnalysisSemantic proximity Read ↗

Contribution of Glutathione-S-Transferases Polymorphism and Risk of Coronary Artery Diseases: A Meta-Analysis.Semantic proximity Read ↗

Polymorphisms in the NQO1, GSTT and GSTM genes are associated with coronary heart disease and biomarkers of oxidative stress.Semantic proximity Read ↗

The importance of polymorphisms in the genes encoding glutathione S-transferase isoenzymes in development of selected cancers and cardiovascular diseases.Semantic proximity Read ↗

The association of glutathione S-transferase T1 and M1 deletions with myocardial infarction.Semantic proximity Read ↗

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytesSemantic proximity Read ↗

Genotype-phenotype associations between chymase and angiotensin-converting enzyme gene polymorphisms in chronic systolic heart failure patients.Semantic proximity Read ↗

The common variant in the GSTM1 and GSTT1 genes is related to markers of oxidative stress and inflammation in patients with coronary artery disease: a case-only study.Semantic proximity Read ↗

An updated meta-analysis showed smoking modify the association of GSTM1 null genotype on the risk of coronary heart disease.Semantic proximity Read ↗

Interaction between GSTM1 genotype and IL-6 on mortality in older adults: results from the ilSIRENTE study.Semantic proximity Read ↗

Relation between glutathione S-transferase genes (GSTM1, GSTT1, and GSTP1) polymorphisms and clinical manifestations of sickle cell disease in Egyptian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.