Article
Role of CYP1A1 haplotypes in modulating susceptibility to coronary artery disease.
Indian journal of biochemistry & biophysics - 1 Oct 2012
Lakshmi Sana Venkata Vijaya, Naushad Shaik Mohammad, Saumya Kankanala, Rao Damera Seshagiri, Kutala Vijay Kumar
Abstract excerpt
To investigate the role of cytochrome P450 1A1 (CYP1A1) haplotypes in modulating susceptibility to coronary artery disease (CAD), a case-control study was conducted by enrolling 352 CAD cases and 282 healthy controls. PCR-RFLP, multiplex PCR, competitive ELISA techniques were employed for the analysis of CYP1A1 [ml (T-->C), m2 (A-->G) and m4 (C-->A)] haplotypes, glutathione-S-transferase (GST)T1/GSTM1 null...
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