Article
T1 and M1 polymorphism in glutathione S-transferase gene and coronary artery disease in North Indian population.
Indian journal of medical sciences - 1 Dec 2004
Girisha K M, Gilmour A, Mastana S, Singh V P, Sinha N, Tewari S, Ramesh V, Sankar V H, Agrawal S
Abstract excerpt
BACKGROUND: DNA damage has been found to play an important role in atherosclerosis and coronary artery disease. Genetic polymorphisms of the genes coding for enzymes involved in the metabolism of genotoxins result in different phenotypes with respect to their ability to detoxify these agents. In the present study the contribution of the polymorphism in the glutathione S-transferase gene to the development of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
