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Article

Development and evaluation of an improved mouse model of meningococcal colonization.

Infection and immunity - 1 Apr 2003

Yi Kyungcheol, Stephens David S, Stojiljkovic Igor

Abstract excerpt

Studies of meningococcal pathogenesis have been severely restricted due to the absence of an adequate animal model. Given the significance of iron in meningococcal pathogenesis, we developed a model of Neisseria meningitidis colonization in outbred adult mice that included daily administration of iron dextran. While receiving iron, the animals were inoculated intranasally with the initial doses of bacterial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12654800
DOI: 10.1128/IAI.71.4.1849-1855.2003
PMCID: PMC152098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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