Article
In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.
PLoS pathogens - 1 Jan 2013
Johswich Kay O, McCaw Shannon E, Islam Epshita, Sintsova Anna, Gu Angel, Shively John E, Gray-Owen Scott D
Abstract excerpt
Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances. Understanding the meningococcal lifestyle within the nasopharyngeal mucosa, a phase of infection that is prerequisite for disease, has been hampered by the lack of animal models. Herein, we compare mice expressing the four different human carcinoembryonic...
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