Article
Analysis of TbpA and TbpB functionality in defective mutants of Neisseria meningitidis.
Journal of medical microbiology - 1 Sept 1998
Pintor M, Gómez J A, Ferrón L, Ferreirós C M, Criado M T
Abstract excerpt
Iron uptake analysis suggested that the Neisseria meningitidis transferrin (Tf) binding proteins, TbpA and TbpB, form only one type of receptor complex. Mutants defective in the synthesis of either TbpA or TbpB, but not defective in both proteins, can bind Tf, suggesting that both proteins are su...
Topics
- Antibodies, Blocking
- Carrier Proteins
- Gene Expression Regulation, Bacterial
- Humans
- Iron
- Iron Radioisotopes
- Iron-Binding Proteins
- Kinetics
- Mutation
- Neisseria meningitidis
- Receptors, Transferrin
- Transferrin
- Transferrin-Binding Proteins