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Article

Identification of novel single nucleotide polymorphisms within the NOTCH4 gene and determination of association with MHC alleles.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2003

Tazi-Ahnini R, Timms J M, Cox A, Wilson A G

Abstract excerpt

Mapping of disease susceptibility loci within the MHC has been partly hampered by the high degree of polymorphism of the HLA genes and the high level of linkage disequilibrium (LD) between markers within the MHC region. It is therefore important to identify new markers and determine the level of LD between HLA alleles and non-HLA genes. The NOTCH4 gene lies at the centromeric end of the MHC class III region,...

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Share to NOTCH4 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Major Histocompatibility Complex

Share to Polymorphism, Single Nucleotide

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Share to Receptor, Notch4

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Source

Identifiers

PMID: 12648276
DOI: 10.1046/j.1365-2370.2003.00364.x

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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Identification of novel single nucleotide polymorphisms within the NOTCH4 gene and determination of association with MHC alleles.PMID 12648276Read ↗

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A re-review of the association between the NOTCH4 locus and schizophrenia.Semantic proximity Read ↗

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Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families.Semantic proximity Read ↗

Is NOTCH4 associated with schizophrenia?Semantic proximity Read ↗

Five NOTCH4 polymorphisms show weak evidence for association with schizophrenia: evidence from meta-analyses.Semantic proximity Read ↗

Notch4, a non-HLA gene in the MHC is strongly associated with the most severe form of alopecia areata.Semantic proximity Read ↗

A review and re-evaluation of an association between the NOTCH4 locus and schizophrenia.Semantic proximity Read ↗

No evidence for association between NOTCH4 and schizophrenia in a large family-based and case-control association analysis.Semantic proximity Read ↗

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