Article
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy.
The Journal of allergy and clinical immunology - 1 Mar 2003
Donfack Joseph, Kogut Paul, Forsythe Sean, Solway Julian, Ober Carole
Abstract excerpt
BACKGROUND: Muscarinic acetylcholine receptors are members of the superfamily of G protein-coupled, 7 transmembrane- spanning proteins. They are important in the development of airway hyperresponsiveness. In the lung the M3 receptor, encoded by the cholinergic receptor muscarinic 3 gene, is present in airway smooth muscle and mediates smooth muscle contraction. OBJECTIVE: We considered the cholinergic receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
