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Article

Lack of association of histamine-N-methyltransferase (HNMT) polymorphisms with asthma in the Indian population.

Journal of human genetics - 1 Jan 2005

Sharma Shilpy, Mann Deepti, Singh Tej Pratap, Ghosh Balaram

Abstract excerpt

Histamine plays a major role in allergic disorders, including asthma. A major pathway of histamine biotransformation in the lungs is mediated by histamine N-methyltransferase (HNMT). We investigated the association of a functional SNP C314T; a SNP A929G, a (CA)n repeat in intron 5, and a novel (CA)n repeat (BV677277), 7.5 kb downstream of the HNMT gene with asthma and its associated traits such as total serum IgE...

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Source

Identifiers

PMID: 16205835
DOI: 10.1007/s10038-005-0302-4

Genes

HNMT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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