Article
Mutation screening of the muscarinic M(2) and M(3) receptor genes in normal and asthmatic subjects.
British journal of pharmacology - 1 May 2001
Fenech A G, Ebejer M J, Felice A E, Ellul-Micallef R, Hall I P
Abstract excerpt
1. Muscarinic receptors are important in the development of airway hyperresponsiveness, and dysfunction of these receptors has been suggested to be present in asthma. 2. The human muscarinic M(2) and M(3) receptor genes were screened for polymorphic variation using single-stranded conformation polymorphism (SSCP) analysis, complemented by direct fluorescent sequencing. Forty-six random DNA samples and 46...
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