Article
CHRM2 but not CHRM1 or CHRM3 polymorphisms are associated with asthma susceptibility in Mexican patients.
Molecular biology reports - 1 Jan 2014
Jiménez-Morales Silvia, Jiménez-Ruíz Juan Luis, Del Río-Navarro Blanca Estela, Navarro-Olivos Efraín, Escamilla-Guerrero Guillermo, Savan Ram, Dean Michael, Orozco Lorena
Abstract excerpt
Asthma is a complex disease for which genetic predisposition has been widely documented. Considerable evidence supports the hypothesis that polymorphisms in the muscarinic-cholinergic (CHRM) genes could be involved in asthma pathogenesis, bronchial hyperresponsiveness, and mucus secretion. To determine whether single nucleotide polymorphisms (SNPs) or haplotypes in CHRM1, CHRM2, or CHRM3 are associated with...
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