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Article

The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.

Diabetologia - 1 Jan 2003

Vidal J, Verchere C Bruce, Andrikopoulos S, Wang F, Hull R L, Cnop M, Olin K L, LeBoeuf R C, O'Brien K D, Chait A, Kahn S E

Abstract excerpt

AIMS/HYPOTHESIS: Islet amyloid deposits are present in over 85% of Type 2 diabetic patients and have been suggested to be pathogenic. The mechanism that converts islet amyloid polypeptide (IAPP), the unique component of these deposits, into amyloid fibrils in vivo is not known. The amino acid seq...

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Share to Amyloid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Intolerance

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Source

Identifiers

PMID: 12637985
DOI: 10.1007/s00125-002-0984-5

Genes

IAPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12637985-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.PMID 12637985Read ↗

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