Article
Reb1p-dependent DNA bending effects nucleosome positioning and constitutive transcription at the yeast profilin promoter.
The Journal of biological chemistry - 16 May 2003
Angermayr Michaela, Oechsner Ulrich, Bandlow Wolfhard
Abstract excerpt
The molecular basis of constitutive gene activation is largely unknown. The yeast profilin gene (PFY1), encoding a housekeeping component of the actin cytoskeleton, is constitutively transcribed at a moderate level. The PFY1 promoter dispenses with classical transactivators and a consensus TATA box; however, it contains a canonic site for the abundant multifunctional nuclear factor rDNA enhancer-binding protein...
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