Article
A nucleosome-free dG-dC-rich sequence element promotes constitutive transcription of the essential yeast RIO1 gene.
Biological chemistry - 1 Sept 2003
Angermayr Michaela, Schwerdffeger Kerstin, Bandlow Wolfhard
Abstract excerpt
RIO1 is an essential gene that encodes a protein serine kinase and is transcribed constitutively at a very low level. Transcriptional activation of RIO1 dispenses with a canonical TATA box as well as with classical transactivators or specific DNA-binding factors. Instead, a dG-dC-rich sequence element, that is located 40 to 48 bp upstream the single site of mRNA initiation, is essential and presumably constitutes...
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