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Article

Promoter nucleosome organization shapes the evolution of gene expression.

PLoS genetics - 1 Jan 2012

Rosin Dalia, Hornung Gil, Tirosh Itay, Gispan Ariel, Barkai Naama

Abstract excerpt

Understanding why genes evolve at different rates is fundamental to evolutionary thinking. In species of the budding yeast, the rate at which genes diverge in expression correlates with the organization of their promoter nucleosomes: genes lacking a nucleosome-free region (denoted OPN for "Occupied Proximal Nucleosomes") vary widely between the species, while the expression of those containing NFR (denoted DPN...

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Identifiers

PMID: 22438828
DOI: 10.1371/journal.pgen.1002579
PMCID: PMC3305400

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