Article
An assessment of the efficiency of PrPsc detection in rectal mucosa and third-eyelid biopsies from animals infected with scrapie.
Veterinary microbiology - 27 Jan 2011
Monleón Eva, Garza Ma Carmen, Sarasa Rocío, Alvarez-Rodriguez Javier, Bolea Rosa, Monzón Marta, Vargas M Antonia, Badiola Juan José, Acín Cristina
Abstract excerpt
In classical scrapie, detection of PrPsc on lymphoreticular system is used for the in vivo and post mortem diagnosis of the disease. However, the sensitivity of this methodology is not well characterised because the magnitude and duration of lymphoid tissue involvement can vary considerably. The aim of the present study was to evaluate the efficiency of detecting PrPsc in rectal mucosa and third-eyelid biopsies....
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