Article
On confidence intervals for genotype relative risks and attributable risks from case parent trio designs for candidate-gene studies.
Human heredity - 1 Jan 2005
Franke Daniel, Philippi Anne, Tores Frédéric, Hager Jörg, Ziegler Andreas, König Inke R
Abstract excerpt
Scherag et al. [Hum Hered 2002;54:210-217] recently proposed point estimates and asymptotic as well as exact confidence intervals for genotype relative risks (GRRs) and the attributable risk (AR) in case parent trio designs using single nucleotide polymorphism (SNP) data. The aim of this study wa...
Topics
- Confidence Intervals
- Family
- Gene Frequency
- Genetic Markers
- Genotype
- Humans
- Models, Genetic
- Monte Carlo Method
- Nuclear Family
- Polymorphism, Single Nucleotide
- Probability
- Risk