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Article

Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50.

The Journal of biological chemistry - 16 May 2003

Rochdi Moulay Driss, Parent Jean-Luc

Abstract excerpt

In the present report, we investigated the effect of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) expression on the agonist-induced internalization of the thromboxane A(2) beta receptor (TPbeta receptor). Interestingly, we found that EBP50 almost completely blocked TPbeta receptor internalization, which could not be reversed by overexpression of G protein-coupled receptor (GPCR) kinases and arrestins....

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Identifiers

PMID: 12626493
DOI: 10.1074/jbc.M210319200

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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