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Article

DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter.

The Journal of biological chemistry - 9 May 2003

Li Yuxin, Xie Mingxing, Song Xiulong, Gragen Sarah, Sachdeva Karuna, Wan Yinsheng, Yan Bingfang

Abstract excerpt

Human DEC (differentially expressed in chondrocytes), mouse STRA (stimulated with retinoic acid), and rat SHARP (split and hairy related protein) proteins constitute a new and structurally distinct class of the basic helix-loop-helix proteins. In each species, two members are identified with a sequence identity of >90% in the basic helix-loop-helix region and approximately 40% in the total proteins, respectively....

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 12624110
DOI: 10.1074/jbc.M300596200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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