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Article

Clusterin, a Novel DEC1 Target, Modulates DNA Damage–Mediated Cell Death

12 Jul 2018

Abstract excerpt

Abstract Differentiated embryonic chondrocyte expressed gene 1 (DEC1, also known as Sharp2/Stra13/BHLHE40) is a basic helix–loop–helix transcription factor that plays an important role in circadian rhythms, cell proliferation, apoptosis, cellular senescence, hypoxia response, and epithelial-to-mesenchymal transition of tumor cells. Secretory clusterin (sCLU) is a cytoprotective protein that guards against...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30002194
DOI: 10.1158/1541-7786.mcr-18-0070

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