Article
N-cadherin is essential for retinal lamination in the zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2003
Erdmann Bettina, Kirsch Frank-P, Rathjen Fritz G, Moré Margret I
Abstract excerpt
N-cadherin is one of the major Ca(2+)-dependent cell adhesion proteins in the developing nervous system. Here, we analyze eye development in the zebrafish N-cadherin loss-of-function mutant parachute(paR2.10) (pac(paR2.10)). The zebrafish visual system is fully developed by the time pac(paR2.10) mutants show lethality at day 5. Already at 24 hr postfertilization (hpf), mutant retinal cells are more disorganized...
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