Article
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites.
Development (Cambridge, England) - 1 Jun 2003
Masai Ichiro, Lele Zsolt, Yamaguchi Masahiro, Komori Atsuko, Nakata Asuka, Nishiwaki Yuko, Wada Hironori, Tanaka Hideomi, Nojima Yasuhiro, Hammerschmidt Matthias, Wilson Stephen W, Okamoto Hitoshi
Abstract excerpt
The complex, yet highly ordered and predictable, structure of the neural retina is one of the most conserved features of the vertebrate central nervous system. In all vertebrate classes, retinal neurons are organized into laminae with each neuronal class adopting specific morphologies and patterns of connectivity. Using genetic analyses in zebrafish, we demonstrate that N-cadherin (Ncad) has several distinct and...
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